Product Name :
CREBtide
CAS NO. :
149155-45-3
Formula :
C73H129N29O19
Molecular Weight::
1716.99
Target:
PKA
Serial Number:
Lys-Arg-Arg-Glu-Ile-Leu-Ser-Arg-Arg-Pro-Ser-Tyr-Arg-OH
Short serial number :
KRREILSRRPSYR
Purity:
95%
Description :
CREBtide, a synthetic 13 amino acid peptide, has been reported as a PKA substrate.
References:
[1]. Wu J, et al. A microPLC-based approach for determining kinase-substrate specificity. Assay Drug Dev Technol. 2007 Aug;5(4):559-66. [2]. Colbran JL, et al. cAMP-dependent protein kinase, but not the cGMP-dependent enzyme, rapidly phosphorylates delta-CREB, and a synthetic delta-CREB peptide. Biochem Cell Biol. 1992 Oct-Nov;70(10-11):1277-82. [3]. Harum KH, et al. Cognitive impairment in Coffin-Lowry syndrome correlates with reduced RSK2 activation. Neurology. 2001 Jan 23;56(2):207-14.
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