AKT/PKB/Rac- Protein Kinase Substrate | DNA_ Alkylatingdna-alkylating.com

Product Name :
AKT/PKB/Rac- Protein Kinase Substrate

CAS NO. :
324029-01-8

Formula :
C74H114N28O20

Molecular Weight::
1715.87

Target:
Akt

Serial Number:
Ala-Arg-Lys-Arg-Glu-Arg-Thr-Tyr-Ser-Phe-Gly-His-His-Ala-OH

Short serial number :
ARKRERTYSFGHHA

Purity:
95%

Description :
AKTide-2T TFA is an excellent in vitro substrate for AKT and shows competitive inhibition of histone H2B phosphorylation with a Ki of 12 nM. AKTide-2T TFA mimics the optimal phosphorylation sequence of Akt and is an inhibitory peptide with the wildtype AKTide lacking Thr in the S22 position.

References:
[1]. T Obata,et al. Peptide and protein library screening defines optimal substrate motifs for AKT/PKB. J Biol Chem. 2000 Nov 17;275(46):36108-15. [2]. Madhavi J Rane, et al. Heat shock protein 27 controls apoptosis by regulating Akt activation. J Biol Chem. 2003 Jul 25;278(30):27828-35.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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