Product Name :
[Tyr22] – CGRP (22 – 37), rat
CAS NO. :
198277-54-2
Formula :
C82H120N20O25
Molecular Weight::
1785.99
Target:
CGRP Receptor; Adenylate Cyclase
Serial Number:
Tyr-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2
Short serial number :
YVKDNFVPTNVGSEAF-NH2
Purity:
≥95%
Description :
[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat is a fragments 22-37 of rat calcitonin gene related peptide (CGRP), targeting CGRP receptor and adenylate cyclase. Calcitonin is mainly produced by thyroid C cells while CGRP is secreted and stored in the nervous system.
References:
[1]. Jia S, et al. Calcitonin gene-related peptide enhances osteogenic differentiation and recruitment of bone marrow mesenchymal stem cells in rats. Exp Ther Med. 2019 Aug;18(2):1039-1046. [2]. Russell FA, et al. Calcitonin gene-related peptide: physiology and pathophysiology. Physiol Rev. 2014 Oct;94(4):1099-142. [3]. Heino P, et al. Binding of CGRP analogs and their effect on adenylate cyclase activity in porcine iris-ciliary body. J Ocul Pharmacol Ther. 1998 Dec;14(6):543-54.
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