Product Name :
MMP-26 Substrate
CAS NO. :
256394-92-0
Formula :
C49H68O15N14
Molecular Weight::
1093.15
Target:
Fluorescent Dye
Serial Number:
MCA-Pro-Leu-Ala-Nva-Dap(Dnp)-Ala-Arg-NH2
Short serial number :
Mca-PLA-Nva-Dap(Dnp)-AR-NH2
Purity:
95%
Description :
Among the fluorescent peptide substrates analyzed, the FRET substrate Mca-Pro-Leu-Ala-Nva-Dpa-Ala-Arg-NH₂ displayed the highest specificity constant with MMP-26 (kcat/Km = 3.0 · 10⁴ M⁻¹s⁻¹, pH 7.5, T = 25 °C). The fluorescence was measured at an excitation wavelength of 328 nm and emission wavelength of 393 nm.
References:
[1]. Hyun I Park, et al. Peptide substrate specificities and protein cleavage sites of human endometase/matrilysin-2/matrix metalloproteinase-26. J Biol Chem
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