Fitc-Acp-YVADAP-K(Dnp) | DNA_ Alkylatingdna-alkylating.com

Product Name :
Fitc-Acp-YVADAP-K(Dnp)

CAS NO. :
1926163-32-7

Formula :
C68H78N12O21S1

Molecular Weight::
1431.48

Target:
others

Serial Number:
5FITC-Ahx-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH

Short serial number :
5FITC-Ahx-YVADAP-K(Dnp)-OH

Purity:
95%

Description :
FITC-YVADAPK(Dnp) is a specific FRET substrate for the determination of caspase-1 and caspase-1 like enzyme activities. Cleavage of FITC-YVADAPK(Dnp) at the P1 Asp residue results in a continuous fluorescent assay. It is useful both in FACS and fluorescence microscopy experiments. Caspase-3 is only weakly active using this substrate. The cleavage product FITC-YVAD can be used as reference substance.

References:
[1]. Rojewski MT, et al. Depolarization of mitochondria and activation of caspases are common features of arsenic(III)-induced apoptosis in myelogenic and lymphatic cell lines. Chem Res Toxicol. 2004 Jan;17(1):119-28.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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