Product Name :
Z-LRGG-AMC
CAS NO. :
167698-68-2
Formula :
C34H44O8N8
Molecular Weight::
692.76
Target:
Biochemical Assay Reagents
Serial Number:
Cbz-Leu-Arg-Gly-Gly-AMC
Short serial number :
Z-LRGG-AMC
Purity:
95%
Description :
Z-LRGG-AMC is a fluorogenic substrate for isopeptidase T (IPaseT) and other ubiquitin C-terminal hydrolases (UCHs) based on the C-termini of ubiquitin with a kcat/Km value of 18 M⁻¹s⁻¹. Together with our product I-1690 it forms the basis of continuous assays for precise mechanistic studies or microtiter plate assays for high-throughput inhibitor screening. LRGG is the preferred substrate sequence of the human deSUMOylating enzymes SENP6 and 7. Stock solutions of Boc-LRGG-AMC are best prepared in DMSO.
References:
[1]. Wang L, et al. Structural and biochemical characterization of SADS-CoV papain-like protease 2. Protein Sci. 2020 May;29(5):1228-1241.
Related websites: https://www.medchemexpress.com/antibodies.html
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