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Product Name :
Myristoyl-Lys-Arg-Thr-Leu-Arg

CAS NO. :
125678-68-4

Formula :
C42H82O8N12

Molecular Weight::
883.18

Target:
PKC

Serial Number:
Myristicacid-Lys-Arg-Thr-Leu-Arg

Short serial number :
Myristicacid-KRTLR

Purity:
95%

Description :
The myristylated pentapeptide Myr-KRTLR is an effective inhibitor of the protein kinase C (PKC)-catalyzed histone phosphorylation (inhibitory constant, IC₅₀ = 75 µM). It competes with the phosphoacceptor substrate of PKC and interacts with the phospholipid cofactor of the enzyme.

References:
[1]. Ioannides CG, et, al. Inhibition of IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat by a novel peptide inhibitor of protein kinase C. Cell Immunol. 1990 Nov;131(1):242-52.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna