Cys(NPys)-Arg9-NH2 | DNA_ Alkylatingdna-alkylating.com

Product Name :
Cys(NPys)-Arg9-NH2

CAS NO. :
1417221-06-7

Formula :
C62H118N40O12S2

Molecular Weight::
1679.99

Target:
others

Serial Number:
Cys(Npys)-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-NH2

Short serial number :
C(Npys)-RRRRRRRRR-NH2

Purity:
95%

Description :
Cell-permeable nonaarginine amide, which can be easily conjugated to a cargo molecule, e.g. by maleimide-thiol coupling.It is a peptide composed of 9 arginine residues synthesized from an activated cysteine residue C(Npys), where Npys is 3-Nitro-2-pyridinesulfenyl protective cysteine. The S(Npys) group of this cysteine-containing 9R is capable of reacting selectively with the free thiol group of another cysteine-containing peptide to form an unsymmetrical disulfide bond. Coupling of sulfhydrils has been studied as an effective means to deliver/release therapeutic agents such as siRNA in the reducing environment within the cell.

References:
[1]. Bilichak A, et al. Intracellular delivery of fluorescent protein into viable wheat microspores using cationic peptides. Front Plant Sci. 2015 Aug 28;6:666.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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