Product Name :
Abz-Ser-Pro-3-nitro-Tyr
CAS NO. :
553644-01-2
Formula :
C24H27N5O9
Molecular Weight::
529.50
Target:
Angiotensin-converting Enzyme (ACE)
Serial Number:
Abz-Ser-Pro-Tyr(3NO2)-OH
Short serial number :
Abz-SP-Y(3NO2)
Purity:
95%
Description :
Selective substrate for angiotensin-converting enzyme 2 (ACE2), an ACE homolog which differs in its specificity and physiological role from ACE. The internally quenched fluorescent (FRET) substrate is potentially useful in applications such as high-throughput screening of ACE2 inhibitors (Km = 23 µM, kcat/Km = 3.5 · 10⁴ M⁻¹s⁻¹).
References:
[1]. Fernández-Atucha A, et al. Sex differences in the aging pattern of renin-angiotensin system serum peptidases. Biol Sex Differ. 2017 Feb 3;8:5.
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