β-Secretase SubstrateⅡ | DNA_ Alkylatingdna-alkylating.com

Product Name :
β-Secretase SubstrateⅡ

CAS NO. :
186142-28-9

Formula :
C50H78N14O19

Molecular Weight::
1179.24

Target:
Beta-secretase

Serial Number:
Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-OH

Short serial number :
SEVNLDAEFR

Purity:
95%

Description :
This peptide substrate corresponds to the ‘Swedish’ Lys-Met/Asn-Leu (K670N/M671L) mutation of the amyloid precursor protein (APP) β-secretase cleavage site. It has been used for assaying β-secretase activity.

References:
[1]. Machálková M, et al. A label-free MALDI TOF MS-based method for studying the kinetics and inhibitor screening of the Alzheimer’s disease drug target β-secretase. Anal Bioanal Chem. 2018 Nov;410(28):7441-7448.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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