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Product Name :
cyclo(GRGDSP)

CAS NO. :
135432-37-0

Formula :
C22H35N9O9

Molecular Weight::
569.57

Target:
Integrin

Serial Number:
cyclo(Gly-Arg-Gly-Asp-Ser-Pro)(main chain cyclo)

Short serial number :
cyclo(GRGDSP)(main chain cyclo)

Purity:
95%

Description :
c(GRGDSP) is a cyclic RGD peptide. It stimulates constriction in rat afferent arteriole. It has been used for the targeted delivery of cisplatin. It could be shown, that c(RGDSP) inhibits the adhesion of mouse B16 melanoma cells onto fibronectin-coated wells.

References:
[1]. Kumagai H, et al. Effect of cyclic RGD peptide on cell adhesion and tumor metastasis. Biochem Biophys Res Commun. 1991 May 31;177(1):74-82.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: DNA_ Alkylatingdna