Product Name :
[Sar1,Ile4,8]-Angiotensin II
CAS NO. :
185461-45-4
Formula :
C43H75N13O9
Molecular Weight::
918.15
Target:
Angiotensin Receptor
Serial Number:
Sar-Arg-Val-Ile-Ile-His-Pro-Ile
Short serial number :
{Sar}-RVIIHP
Purity:
≥95%
Description :
(Sar1,Ile4,8)-Angiotensin II is a functionally selective angiotensin II type 1 receptor (AT1R) agonist. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated insulin receptor (IR) signaling and glycogen synthesis. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated phosphorylation of Akt and GSK3α/β.
References:
[1]. Sanni SJ, et al. [Sar1, Ile4, Ile8]-angiotensin II Potentiates Insulin Receptor Signalling and Glycogen Synthesis in Hepatocytes. Basic Clin Pharmacol Toxicol. 2018 May;122(5):460-469.
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