Angiotensin I, human | DNA_ Alkylatingdna-alkylating.com

Product Name :
Angiotensin I, human

CAS NO. :
484-42-4

Formula :
C62H89N17O14

Molecular Weight::
1296.5

Target:
Endogenous Metabolite

Serial Number:
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu

Short serial number :
DRVYIHPFHL

Purity:
≥95%

Description :
This human Angiotensin I (Ang I) sequence also corresponds to horse, sheep, pig, and rat Ang I. Ang I is cleaved to Ang II by the angiotensin-converting enzyme (ACE). There is also evidence for non-angiotensin-converting enzyme-dependent conversion of Ang I to Ang II. Human chymase efficiently converts the 10-mer Ang I to the 8-mer hormone Ang II by splitting the Phe8-His9 bond in Ang I.

References:
[1]Ref: Lundequist, A. et al. J. Biol. Chem. 279, 32339 (2004); [2] Olson, S. et al. Am. J. Physiol. Lung. Cell Mol. Physiol. 287, L559 (2004); [3]Sanker, S. et al. J. Biol. Chem. 272, 2963 (1997).

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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