Product Name :
Fibronectin tetrapeptide
CAS NO. :
91037-65-9
Formula :
C15H27N7O8
Molecular Weight::
433.42
Target:
Integrin
Serial Number:
Arg-Gly-Asp-Ser
Short serial number :
RGDS
Purity:
95%
Description :
Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1.
References:
[1]. Grigoriou V, et al. Apoptosis and survival of osteoblast-like cells are regulated by surface attachment. J Biol Chem. 2005 Jan 21;280(3):1733-9. [2]. Moon C, et al. Synthetic RGDS peptide attenuates lipopolysaccharide-induced pulmonary inflammation by inhibiting integrin signaled MAP kinase pathways. Respir Res. 2009 Mar 9;10:18. [3]. Yin X, et al. Synthetic RGDS peptide attenuated lipopolysaccharide/D-galactosamine-induced fulminant hepatic failure in mice. J Gastroenterol Hepatol. 2014 Jun;29(6):1308-15. [4]. Aguzzi MS, et al. Intracellular targets of RGDS peptide in melanoma cells. Mol Cancer. 2010 Apr 22;9:84.
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
p53 (acetyl K382) Rabbit mAb In Vivo
c-Kit Rabbit mAb Technical Information
SpI1 Antibody (YA117): SpI1 Antibody (YA117) is a non-conjugated and Rabbit origined monoclonal antibody about 31 kDa, targeting to PU.1/Spi1. It can be used for WB,IHC-P,FC assays with tag free, in the background of Human.
