Product Name :
Ac-DRLDS
CAS NO. :
153959-57-0
Formula :
C25H42O12N8
Molecular Weight::
646.65
Target:
Serial Number:
Ac-Asp-Arg-Leu-Asp-Ser
Short serial number :
Ac-DRLDS
Purity:
95%
Description :
The acetylated pentapeptide Ac-DRLDS inhibits tumor cell adhesion to laminin, fibronectin, vitronectin, and RGDS-IgG substrates. Ac-DRLDS also inhibits tumor cell adhesion to CS-1-IgG as well as the CS-1-derived peptide (EILDV), in a concentration-dependent manner. Although the inhibitory effect was less than that of EILDV, this peptide retains the properties of both RGDS and EILDV.
References:
[1]. Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives. [2]. Antimetastatic activities of synthetic Arg-Gly-Asp-Ser (RGDS) and Arg-Leu-Asp-Ser (RLDS) peptide analogues and their inhibitory mechanisms.
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