Tumor Targeted Pro-Apoptotic Peptide、NGR Peptide 1 | DNA

Product Name :
Tumor Targeted Pro-Apoptotic Peptide、NGR Peptide 1

CAS NO. :
1926163-30-5

Formula :
C94H174N32O22S2

Molecular Weight::
2168.72

Target:
Apoptosis

Serial Number:
Cys-Asn-Gly-Arg-Cys-Gly-Gly-DLys-DLeu-DAla-DLys-DLeu-DAla-DLys-DLys-DLeu-DAla-DLys-DLeu-DAla-DLys-NH2(Disulfide Bridge:Cys1-Cys5)

Short serial number :
CNGRCGG-{DLys-DLeu-DAla-DLys-DLeu-DAla-DLys-DLys-DLeu-DAla-DLys-DLeu-DAla-DLys}-NH2(Disulfide Bridge:Cys1-Cys5)

Purity:
95%

Description :
It is a peptide with NGR (Asn-Gly-Arg) motif, which has a disulfide bridge linking cys1 to cys5, and is known to have antibacterial properties in addition to the presence of KLA sequences. It binds to CD13 on tumor cells and shows strong cytotoxicity and activity against tumor cells. It can deliver various anti-tumor compounds and virus particles to tumor vessels.

References:
[1]. Ellerby HM, et al. Anti-cancer activity of targeted pro-apoptotic peptides. Nat Med. 1999 Sep;5(9):1032-8.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: DNA_ Alkylatingdna

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