Anthranilyl-HIV Protease Substrate | DNA_ Alkylatingdna-alkylating.com

Product Name :
Anthranilyl-HIV Protease Substrate

CAS NO. :
133233-38-2

Formula :
C43H65N13O11

Molecular Weight::
940.06

Target:
others

Serial Number:
Abz-Thr-Ile-Nle-Phe(4NO2)-Gln-Arg-NH2

Short serial number :
Abz-TI-Nle-F(4NO2)-QR-NH2

Purity:
95%

Description :
This hexapeptide FRET substrate is derived from the p24/p15 cleavage site of the viral gag-pol poly-protein. A simple, continuous fluorometric assay for HIV protease has been developed, which allows the screening of potential HIV protease inhibitors. Values for Km (2.1 μM) and kcat (7.4 s⁻¹) were calculated from steady-state data at a low concentration of the enzyme. Excitation at 280 nm, emission at > 435 nm.

References:
[1]. Porter DJ, et al. Effectors of HIV-1 protease peptidolytic activity. Biochemistry. 2001 Sep 18;40(37):11131-9.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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