Product Name :
[Ala9]Autocamtide2
CAS NO. :
167114-91-2
Formula :
C64H116N22O19
Molecular Weight::
1497.74
Target:
CaMK Autophagy
Serial Number:
Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu-OH
Short serial number :
KKALRRQEAVDAL
Purity:
95%
Description :
Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.
References:
[1]. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. [2]. Ryanodine receptor phosphorylation by CaMKII promotes spontaneous Ca(2+) release events in a rodent model of early stage diabetes: The arrhythmogenic substrate. [3]. Intra-nucleus accumbens administration of the calcium/calmodulin-dependent protein kinase II inhibitor AIP induced antinociception in rats with mononeuropathy.
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