Cadherin Peptide , avian

Description :
Cadherins, also known as calcium-dependent adhesion proteins, are a class of type 1 transmembrane proteins. They play an important role in the cell adhesion process, thus ensuring that cells within tissues are bound together and rely on calcium ions (Ca2+) to function. Cadherin is a synthetic polypeptide that undergoes many post-translational modifications to become proteins that mediate cell-cell adhesion and recognition. Cadherin can act as both a receptor and a ligand. During development, they contribute to the correct positioning of cells and are involved in the separation of different tissue layers and cell migration. E-cadherin (epithelial cadherin) is most expressed in the early stages of development. During the development of the neural plate in the next stage, the expression of N-cadherin (neurocadherin) decreases, and the expression of E-cadherin decreases. Finally, E-, P-, and N-cadherin expressions increased during the development of the notochord and the condensation of somites. After the developmental process, cadherin plays a role in maintaining cell and tissue structure and cell motility.