Product Name :
Hel 13-5
CAS NO. :
177942-21-1
Formula :
C113H204N24O19
Molecular Weight::
2202.98
Target:
others
Serial Number:
Lys-Leu-Leu-Lys-Leu-Leu-Leu-Lys-Leu-Trp-Leu-Lys-Leu-Leu-Lys-Leu-Leu-Leu-OH
Short serial number :
KLLKLLLKLWLKLLKLLL
Purity:
95%
Description :
Highly lipid-soluble α-helical amphiphilic cell-penetrating peptide used in combination with phospholipids for developing pulmonary surfactant model systems. Hel 13-5 also binds to nucleic acids. The CPP is a most efficient DNA and siRNA delivering and transfecting agent.Hel 13-5 is a cell-penetrating peptide that contains Leu and Lys residues in the ratio of 13:5. It binds to DNA and forms alpha-helical structures. It is used as an efficient way for gene transfer into cells and DNA transfection.
References:
[1]. Nakahara H, et al. Pulmonary surfactant model systems catch the specific interaction of an amphiphilic peptide with anionic phospholipid. Biophys J. 2009 Feb 18;96(4):1415-29. [2]. Nakahara H, et al. Langmuir monolayer of artificial pulmonary surfactant mixtures with an amphiphilic peptide at the air/water interface: comparison of new preparations with surfacten (Surfactant TA). Langmuir. 2008 Apr 1;24(7):3370-9.
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