Product Name :
[Ala11,22,28]-VIP (human, bovine, porcine, rat)
CAS NO. :
291524-04-4
Formula :
C139H231N43O39S1
Molecular Weight::
3160.65
Target:
Serial Number:
His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Ala-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Ala-Leu-Asn-Ser-Ile-Leu-Ala-NH2
Short serial number :
HSDAVFTDNYARLRKQMAVKKALNSILA-NH2
Purity:
95%
Description :
(Ala11.22.28)-VIP (human, mouse, rat), a highly selective human VPAC1 receptor agonist, shows a 1000-fold higher efficiency in stimulating adenylate cyclase activity from VPAC1 than VPAC2 receptors. It is a valid pharmacological tool for characterizing VPAC1 receptor-mediated events.
References:
[1]. Activation of VPAC1 receptors aggravates early atherosclerosis in hypercholesterolemic apolipoprotein E-deficient mice. [2]. Cutting edge: vasoactive intestinal peptide acts as a potent suppressor of inflammation in vivo by trans-deactivating chemokine receptors.
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