Product Name :
Galnon
CAS NO. :
475115-35-6
Formula :
C40H46O6N4
Molecular Weight::
678.82
Target:
Neuropeptide Y Receptor
Serial Number:
Fmoc-Cha-Lys-AMC
Short serial number :
Fmoc-Cha-K-AMC
Purity:
95%
Description :
Galnon is a non-peptide galanin GAL1 and GAL2 receptor agonist (Ki = 11.7 and 34.1 μM, respectively) with anticonvulsant, anxiolytic, anorectic and amnestic activities. It stimulates insulin release in isolated pancreatic islets from normal and diabetic rats.
References:
[1]. Bartfai T, et, al. Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10470-5. [2]. Rajarao SJR, et, al. Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon. Neuropeptides. 2007 Oct;41(5):307-20.
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