PMX 53 acetate | DNA_ Alkylatingdna-alkylating.com

Product Name :
PMX 53 acetate

CAS NO. :
852629-88-0

Formula :
C47H65N11O7.C2H4O2

Molecular Weight::
956.14

Target:

Serial Number:
Ac-Phe-Orn-Phe-Ala-Trp-Arg.CH3CO2H (Modifications:Ala-4 = D-Ala, Disulfide bridge between Orn2-Arg6)

Short serial number :
Ac-FXPAWR.CH3CO2H (Modifications: Ala-4 = D-Ala, Disulfide bridge between Orn2-Arg6)

Purity:
95%

Description :
PMX 53 is a potent and orally active C5aR(CD88) antagonist and Mas-related gene 2 (MrgX2) agonist. It stimulates MrgX2-mediated mast cell degranulation, inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis, inhibits lung metastasis in a mouse breast cancer model, and reduces atherosclerotic lesions in a mouse model of atherosclerosis.

References:

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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