Product Name :
[DTrp8]-delta-OMelanocyte Stimulating Hormone
CAS NO. :
321351-81-9
Formula :
C74H99N21O16S1
Molecular Weight::
1570.77
Target:
Melanocortin Receptor
Serial Number:
Tyr-Val-Met-Gly-His-Phe-Arg-DTrp-Asp-Arg-Phe-Gly
Short serial number :
YVMGHFRwDRFG
Purity:
95%
Description :
[D-Trp8]-γ-MSH acetate is a selective melanocortin 3 (MC3) receptor agonist (IC50 = 6.7, 340 and 600 nM for human MC3, MC5 and MC4 receptors, respectively). It displays antiinflammatory efficacy in mice bearing a non-functional MC1R (recessive yellow e/e mouse) and these effects are abrogated in the presence of the HO-1 inhibitor ZnPPIX.
References:
[1].Melanocortin modulation of inflammatory cytokine and neuroendocrine responses to endotoxin in the monkey.
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