Product Name :
[Sar1]Angiotensin II
CAS NO. :
51833-69-3
Formula :
C49H71N13O10
Molecular Weight::
1002.17
Target:
Serial Number:
Sar-Arg-Val-Tyr-Ile-His-Pro-Phe
Short serial number :
(NMe)G-RVYIHPF
Purity:
95%
Description :
(Sar1)-Angiotensin II, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. (Sar1)-Angiotensin II binds to brain membrane-rich particles, with a Kd of 2.7 nM. (Sar1)-Angiotensin II can stimulate protein synthesis and cell growth in embryonic chick myocytes.(Sar1)-Angiotensin II acetate is a specific agonist of the angiotensin AT1 receptor that binds to brain membrane-rich particles, with a Kd of 2.7 nM. (Sar1)-Angiotensin II acetate can stimulate protein synthesis and cell growth in embryonic chick myocytes.
References:
[1].Matsoukas JM, et, al. Differences in backbone structure between angiotensin II agonists and type I antagonists. J Med Chem. 1995 Nov 10;38(23):4660-9. [2].Aceto JF, et, al. [Sar1]angiotensin II receptor-mediated stimulation of protein synthesis in chick heart cells. Am J Physiol. 1990 Mar;258(3 Pt 2):H806-13. [3].Millan MA, et, al. Distribution of angiotensin II receptors in the brain of nonhuman primates. Peptides. Mar-Apr 1990;11(2):243-53.
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