Product Name :
Neuropeptide SF (mouse, rat)
CAS NO. :
230960-31-3
Formula :
C40H65N13O10
Molecular Weight::
888.03
Target:
Neuropeptide Y Receptor
Serial Number:
Ser-Leu-Ala-Ala-Pro-Gln-Arg-Phe-NH2
Short serial number :
SLAAPQRF-NH2
Purity:
95%
Description :
Neuropeptide SF (mouse,rat) is a potent neuropeptide FF receptor agonist with Ki values are 48.4 nM and 12.1 nM for NPFF1 and NPFF2, respectively. Neuropeptide SF increases the amplitude of the sustained current of heterologously expressed acid sensing ion channel 3 (ASIC3).Neuropeptide SF (mouse, rat) acetate is a neuropeptide FF receptor agonist (Ki = 48.4 and 12.1 nM for NPFF1 and NPFF2, respectively). NPSF may play a physiologic role in the regulation of such circadian functions as the activity of motor centers and the HPA axis, through the release of CRH.
References:
[1].Miklós Jászberényi, et al. The actions of neuropeptide SF on the hypothalamic-pituitary-adrenal axis and behavior in rats.Regul Pept. 2014 Jan 10;188:46-51. [2].C Gouardères, et al. Quantitative autoradiographic distribution of NPFF1 neuropeptide FF receptor in the rat brain and comparison with NPFF2 receptor by using [125I]YVP and [(125I]EYF as selective radioligands. Neuroscience. 2002;115(2):349-61.
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