Goserelin | DNA_ Alkylatingdna-alkylating.com

Product Name :
Goserelin

CAS NO. :
65807-02-5

Formula :
C59H84N18O14

Molecular Weight::
1269.41

Target:
GnRH Receptor，Apoptosis

Serial Number:
Pyr-His-Trp-Ser-Tyr-DSer(tBu)-Leu-Arg-Pro-AzaGly-NH2

Short serial number :
Pyr-HWSY-DSer(tBu)-LRP-AzaGly-NH2

Purity:
95%

Description :
Goserelin is a gonadotropin releasing hormone agonist with antineoplastic activity. It inhibits estrogen and androgen production and is used predominantly to treat prostate cancer.

References:
[1]. Ning Zhang, et al. Goserelin promotes the apoptosis of epithelial ovarian cancer cells by upregulating forkhead box O1 through the PI3K/AKT signaling pathway. Oncol Rep. 2018 Mar; 39(3): 1034–1042. [2]. Halle C F Moore, et al. Goserelin for ovarian protection during breast-cancer adjuvant chemotherapy. N Engl J Med. 2015 Mar 5;372(10):923-32.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: DNA_ Alkylatingdna

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