Product Name :
Myelin Oligodendrocyte Glycoprotein(35-55), rat MOG(35-55)
CAS NO. :
149635-73-4
Formula :
C118H177N35O29S
Molecular Weight::
2582
Target:
others
Serial Number:
Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys
Short serial number :
MEVGWYRSPFSRVVHLYRNGK
Purity:
≥95%
Description :
Myelin Oligodendrocyte Glycoprotein(35-55), rat MOG(35-55) is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein(35-55), rat MOG(35-55) has encephalitogenic activity and induces T cell proliferative. Myelin Oligodendrocyte Glycoprotein(35-55), rat MOG(35-55) induces Th1 cytokine response as well as relatively high levels of IgG antibodies. Myelin Oligodendrocyte Glycoprotein(35-55), rat MOG(35-55) produces a relapsing-remitting neurological disease with extensive plaque-like demyelination.
References:
[1]. Rich C, et, al. Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice. Eur J Immunol. 2004 May;34(5):1251-61. [2]. Slavin A, et, al. Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein. Autoimmunity. 1998;28(2):109-20. [3]. Giralt M, et, al. Active Induction of Experimental Autoimmune Encephalomyelitis (EAE) with MOG35-55 in the Mouse. Methods Mol Biol. 2018;1791:227-232.
Related websites: https://www.medchemexpress.com/antibodies.html
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