Product Name :
Magainin 2
CAS NO. :
108433-95-0
Formula :
C114H180N30O29S
Molecular Weight::
2466.95
Target:
Melanocortin ReceptorBacterial; Antibiotic; Fungal
Serial Number:
Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser
Short serial number :
GIGKFLHSAKKFGKAFVGEIMNS
Purity:
≥95%
Description :
Magainin 2 assumes an amphiphilic helix when bound to acidic phospholipids, forming a pore composed of a dynamic, peptide-lipid supramolecular complex.
References:
[1]. M Zasloff, et al. Magainins, a class of antimicrobial peptides from Xenopus skin: isolation, characterization of two active forms, and partial cDNA sequence of a precursor. Proc Natl Acad Sci U S A. 1987 Aug;84(15):5449-53. [2]. K Matsuzaki, et al. Magainins as paradigm for the mode of action of pore forming polypeptides. Biochim Biophys Acta. 1998 Nov 10;1376(3):391-400.
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