Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide

Product Name :
Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide

CAS NO. :
819048-44-7

Formula :
C51H72N18O11S2

Molecular Weight::
1177.36

Target:
Melanocortin Receptor

Serial Number:
Ac-D-Arg-Cys-Glu-His-D-Phe-Arg-Trp-Cys-NH2(Disulfide bridge: Cys2-Cys8)

Short serial number :
Ac-{D-Arg}-CEH-{D-Phe}-RWC-NH2 (Disulfide bridge: Cys2-Cys8)

Purity:
≥95%

Description :
Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide is a cyclic octapeptide with MC4R agonism. Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide significantly increases heart rate and blood pressure.

References:
[1]. Doering SR, et al. Discovery of Nanomolar Melanocortin-3 Receptor (MC3R)-Selective Small Molecule Pyrrolidine Bis-Cyclic Guanidine Agonist Compounds Via a High-Throughput “Unbiased” Screening Campaign. J Med Chem. 2021 May 13;64(9):5577-5592. doi: 10.1021/acs.jmedchem.0c02041. Epub 2021 Apr 22. Erratum in: J Med Chem. 2023 May 25;66(10):7063-7065.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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