Product Name :
IL-8 Inhibitor
CAS NO. :
138559-60-1
Formula :
C45H66N18O7S
Molecular Weight::
1003.2
Target:
CXCR
Serial Number:
Ac-Arg-Arg-Trp-Trp-Cys-Arg- NH2
Short serial number :
Ac-RRWWCR-NH2
Purity:
≥95%
Description :
IL-8 Inhibitor, a hexapeptide, is a potent inhibitor of CXC-chemokine receptor (CXCR). IL-8 Inhibitor inhibits neutrophil chemotaxis and activation. Antileukinate can be used for the research of acute inflammation and injury.
References:
[1]. Madhav Bhatia, et al. Treatment with antileukinate, a CXCR2 chemokine receptor antagonist, protects mice against acute pancreatitis and associated lung injury. Regul Pept. 2007 Jan 10;138(1):40-8. [2]. Yuji Fukuno, et al. Chemokine receptor inhibitor, Antileukinate, suppressed ovalbumin-induced eosinophilic inflammation in the airway. Cytokine. 2003 Jun 7;22(5):116-25. [3]. S HayashiY, et al. Antileukinate, a hexapeptide inhibitor of CXC-chemokine receptor, suppresses bleomycin-induced acute lung injury in mice. Lung. 2002;180(6):339-48.
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