Product Name :
Diazepam-Binding Inhibitor Fragment, human
CAS NO. :
104360-70-5
Formula :
C91H148N26O32S
Molecular Weight::
2150.41
Target:
Serial Number:
Gln-Ala-Thr-Val-Gly-Asp-Ile-Asn-Thr-Glu-Arg-Pro-Gly-Met-Leu-Asp-Phe-Thr-Gly-Lys
Short serial number :
QATVGDINTERPGMLDFTGK
Purity:
≥95%
Description :
Peptide fragment corresponding to residues 51-70 of the human diazepam binding inhibitor protein; peripheral benzodiazepine receptor agonist. Induces intracellular Ca2+ increase and phagocytosis in human neutrophils, mainly through a non-peripheral benzodiazepine receptor-mediated mechanism. Also reduces ammonia-induced swelling in cultured astrocytes.
References:
[1] M.Cosentino et al., J. Leukoc. Biol., 67, 637(2000). [2].P.W.Gray et al., Proc. Natl. Acad. Sci. USA, 83, 7547 (1986)
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