Product Name :
IV9 (476 – 484), HIV – 1 RT Epitope
CAS NO. :
Formula :
C46H78N12O12
Molecular Weight::
991.21
Target:
HIV1
Serial Number:
Ile-Leu-Lys-Glu-Pro-Val-His-Gly-Val
Short serial number :
ILKEPVHGV
Purity:
≥95%
Description :
This is a reverse transcriptase (RT) epitope (Pol residues 476-484). Within HIV-1 RT the peptide appears to be the dominant HLA A*0201-restricted epitope. Was used to investigate possible mechanisms behind HIV-1 escape from CTL. IV9 is the actual epitope processed and presented in HIV-1-infected cell lines.
References:
[1].Epitope Escape Mutation and Decay of Human Immunodeficiency Virus Type 1-Specific CTL Responses J Immunol . 2003 Nov 15 ; 171(10) 5372 . [2].IFN-γ Exposes a Cryptic Cytotoxic T Lymphocyte Epitope in HIV-1 Reverse Transcriptase J Immunol . 1999 Jun 15 ; 162(12) 7075. [3].Lack of strong immune selection pressure by the immunodominant, HLA-A 0201-restricted cytotoxic T lymphocyte response in chronic human immunodeficiency virus-1 infection.J Clin Invest . 1998 Jun 01 ; 101(11) 2559.
Related websites: https://www.medchemexpress.com/antibodies.html
Popular product recommendations:
Bcl2 Antibody (YA824)
JNK1 Antibody (YA720)
BMP2 Antibody: BMP2 Antibody is an unconjugated, approximately 13/44 kDa, rabbit-derived, anti-BMP2 polyclonal antibody. BMP2 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, rat, and predicted: chicken, dog, cow, horse, rabbit, sheep background without labeling.
