Guanylin, human | DNA_ Alkylatingdna-alkylating.com

Product Name :
Guanylin, human

CAS NO. :
183200-12-6

Formula :
C58H87N15O21S4

Molecular Weight::
1458.68

Target:
Guanylate Cyclase; Endogenous Metabolite

Serial Number:
Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr- Gly-Cys(Disulfide bridge: Cys4-Cys12, Cys7-Cys15)

Short serial number :
PGTCEICAYAACTGC (Disulfide bridge:Cys4-Cys12;Cys7-Cys15)

Purity:
≥95%

Description :
Guanylin(human), a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism.

References:
[1]. M G Currie, et al. Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc Natl Acad Sci U S A. 1992 Feb 1;89(3):947-51. [2]. J Bełtowski. Guanylin and related peptides. J Physiol Pharmacol. 2001 Sep;52(3):351-75.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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