Product Name :
Exendin (9-39)
CAS NO. :
133514-43-9
Formula :
C149H234N40O47S1
Molecular Weight::
3369.83
Target:
GCGR
Serial Number:
Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
Short serial number :
DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH2
Purity:
≥95%
Description :
Avexitide (Exendin (9-39)) is a specific and competitive GLP-1 receptor antagonist.
References:
[1]. Calabria AC, et al. GLP-1 receptor antagonist exendin-(9-39) elevates fasting blood glucose levels in congenital owing to inactivating mutations in the ATP-sensitive K+ channel. Diabetes. 2012 Oct;61(10):2585-91. [2]. De León DD, et al. Exendin-(9-39) corrects fasting hypoglycemia in SUR-1-/- mice by lowering cAMP in pancreatic beta-cells and inhibiting secretion. J Biol Chem. 2008 Sep 19;283(38):25786-93.
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