Product Name :
Galanin (swine)
CAS NO. :
88813-36-9
Formula :
C146H213N43O40
Molecular Weight::
3210.55
Target:
Neuropeptide Y Receptor
Serial Number:
Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-His-Ala-Ile-Asp-Asn-His-Arg-Ser-Phe-His-Asp-Lys-Tyr-Gly-Leu-Ala-NH2
Short serial number :
GWTLNSAGYLLGPHAIDNHRSFHDKYGLA-NH2
Purity:
≥95%
Description :
Galanin (swine), a neuropeptide, consists of 29 amino acids and contains a C-terminal amidated glycine. Galanin (swine) inhibits basal and stimulated insulin secretion both in vivo and in vitro under a variety of experimental conditions. Galanin (swine) is a galanin receptor agonist with pKis of 9.63, 9.49, 9.02, 8.98, 8.01 and 8.14 at human GAL1, rat GAL1, human GAL2, rat GAL2, human GAL3 and rat GAL3 respectively.
References:
[1]. Branchek TA, et al. Galanin receptor subtypes. Trends Pharmacol Sci. 2000;21(3):109-117. [2]. Ahrén B, et al. Galanin and the endocrine pancreas. FEBS Lett. 1988;229(2):233-237.
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