Product Name :
DiprotinB
CAS NO. :
90614-49-6
Formula :
C16H29N3O4
Molecular Weight::
327.42
Target:
Dipeptidyl Peptidase
Serial Number:
Val-Pro-Leu
Short serial number :
VPL
Purity:
95%
Description :
Diprotin B is a dipeptidyl aminopeptidase IV (DPP IV) inhibitor. The apparent competitive inhibition of DPP-IV by the diprotins is a kinetic artifact, derived from the substrate-like nature of tripeptides containing a penultimate proline residue.
References:
[1]. Rahfeld J, et al. Are diprotin A (Ile-Pro-Ile) and diprotin B (Val-Pro-Leu) inhibitors or substrates of dipeptidyl peptidase IV? Biochim Biophys Acta. 1991 Jan 29;1076(2):314-6. [2]. Hatanaka T, et al. Inhibitory effect of collagen-derived tripeptides on dipeptidylpeptidase-IV activity. J Enzyme Inhib Med Chem. 2014 Dec;29(6):823-8.
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