Product Name :
cyclo(RGDfC)
CAS NO. :
862772-11-0
Formula :
C24H34N8O7S1
Molecular Weight::
578.64
Target:
Integrin
Serial Number:
cyclo(Arg-Gly-Asp-DPhe-Cys)(main chain cyclo)
Short serial number :
cyclo(RGDfC)(main chain cyclo)
Purity:
95%
Description :
Cyclo(Arg-Gly-Asp-D-Phe-Cys) (Cyclo RGDfC), a cyclic RGD peptide which has high affinity to αvβ3, can disrupt cell integrin interactions. Cyclo(Arg-Gly-Asp-D-Phe-Cys) inhibits pluripotent marker expression in embryonic stem cells (ESCs) and the tumorigenic potential of mESCs in vivo. Cyclo(Arg-Gly-Asp-D-Phe-Cys) can be used in the research of tumors.
References:
[1]. Hazenbiller O, et al. Reduction of pluripotent gene expression in murine embryonic stem cells exposed to mechanical loading or Cyclo RGD peptide. BMC Cell Biol. 2017 Nov 14;18(1):32.
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