Product Name :
FTase Inhibitor I
CAS NO. :
149759-96-6
Formula :
C22H38N4O3S2
Molecular Weight::
470.69
Target:
Farnesyl Transferase
Serial Number:
Unk-Phe-Met-OH
Short serial number :
Unk-FM-OH
Purity:
95%
Description :
FTase inhibitor I is a potent and selective farnesyltransferase (FTase) inhibitor with an IC50 of 21 nM, which is 30-fold higher for FTase over geranylgeranyl transferase (GGTase; IC50 = 790 nM).
References:
[1]. A D Cox, et al. The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation. J Biol Chem. 1994 Jul 29;269(30):19203-6.
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