Product Name :
六肽LCKLSL hydrochloride
CAS NO. :
533902-29-3
Formula :
C30H57N7O8S1
Molecular Weight::
675.88
Target:
Others
Serial Number:
Leu-Cys-Lys-Leu-Ser-Leu
Short serial number :
LCKLSL
Purity:
95%
Description :
LCKLSL is a N-terminal hexapeptide and a competitive annexin A2 (AnxA2) inhibitor. LCKLSL potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2. LCKLSL also inhibits the generation of plasmin and has anti-angiogenic roles.
References:
[1].Mallika Valapala, et al. A Competitive Hexapeptide Inhibitor of Annexin A2 Prevents Hypoxia-Induced Angiogenic Events. J Cell Sci. 2011 May 1;124(Pt 9):1453-64.
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