Product Name :
PKCε Inhibitor Peptide
CAS NO. :
182683-50-7
Formula :
C37H65N9O13
Molecular Weight::
843.96
Target:
PKC
Serial Number:
Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr
Short serial number :
EAVSLKPT
Purity:
95%
Description :
Epsilon-V1-2 (ε-V1-2), a PKCε-derived peptide, is a selective PKCε inhibitor. Epsilon-V1-2 inhibits the translocationof PKCε, but not α-, β-, and δPKC.
References:
[1].M Yedovitzky, et al. Translocation inhibitors define specificity of protein kinase C isoenzymes in pancreatic beta-cells. J Biol Chem. 1997 Jan 17;272(3):1417-20.. [2].Yuahn-Sieh Huang, et al. Mechanism of oleic acid-induced gap junctional disassembly in rat cardiomyocytes. J Mol Cell Cardiol. 2004 Sep;37(3):755-66. [3].Tomoyoshi Koyanagi, et al. Pharmacological inhibition of epsilon PKC suppresses chronic inflammation in murine cardiac transplantation model. J Mol Cell Cardiol. 2007 Oct;43(4):517-22.
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