Ab, two. Umi Kalsom Ali, 3. Marlyn Mohammad, four. Ezura Madiana Md. Monoto, 5. M.M. Rahman, 1-3,5: Division of Health-related Microbiology Immunology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras 56000 Kuala Lumpur, Malaysia. four: Division of Household Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras 56000 Kuala Lumpur, Malaysia. Correspondence: Asrul Abdul Wahab, Division of Medical Microbiology Immunology, Faculty of Medicine, The National University of Malaysia, Cheras 56000 Kuala Lumpur, Malaysia. E-mail: asrulwahab@hotmailthe TLR1 Biological Activity infection inside the pregnant woman are essential to be able to avoid adverse outcome. CASE 1: Mrs. ZNA, a 29-year-old Malay housewife, Gravida 4 Para 2+1, came for antenatal booking in the primary care clinic, complaining of polyuria, polydipsia and lethargy for the past 1 week. Dating ultrasound revealed 11 weeks fetus. She was diagnosed with gestational diabetes mellitus (GDM) with fasting blood glucose of 11.0 mmol/L and subsequently referred right here for further management. She also complained of itchiness at the genital region connected with whitish vaginal discharge whereby the high vaginal swab specimen for microbiology culture revealed presence of candida infection. She was subsequently treated appropriately. Routine blood investigations such as hepatitis B, human immunodeficiency virus (HIV) and syphilis serology tests had been done. The serology tests for hepatitis B and HIV have been adverse. Having said that, the speedy plasma reagin (RPR) was reactive at 1:16 titration. The diagnosis of syphilis was confirmed by a positive Syphilis IgG outcome. On additional history, she admitted for the treatment of syphilis in the course of her earlier pregnancy in 2010 at a further hospital. She was provided 3 doses of intramuscular penicillin. Preceding syphilis record showed the RPR titre was 1:8 but no subsequent follow-up.Pak J Med Sci 2015 Vol. 31 No. 1 pjms.pk Received for Publication: Revision Received: Edited by Reviewer: Accepted for Publication:June 26, 2014 July 9, 2014 September 22, 2014 September 29,Asrul Abdul Wahab et al.The diagnosis of syphilis re-infection was produced and she was treated with 2.4 million units of penicillin weekly for 3 doses. Her other health-related issues have been managed accordingly. She was discharged in the ward once the blood sugar level was optimized and continued her adhere to up inside the clinic. Her Aldose Reductase Synonyms husband was counselled for syphilis screening but refused. Consequently, she completed the treatment for syphilis. The second and third trimester ultrasounds revealed no abnormalities. Repeated RPR at 33 weeks of gestation was non-reactive. She delivered a child boy at 38 weeks of gestation via LSCS with birth weight of 4.0 kg. No clinical signs of congenital syphilis noted. Fast Plasma Reagin (RPR) outcome for the infant was nonreactive. She was discharged just after 3 days inside the ward. Post-natal follow up was scheduled for them but she requested to become observed in a further hospital at her hometown. CASE 2: Mrs. TPS is a 21-year-old Chinese housewife, Gravida 1 Para 0, at 31 weeks gestation was admitted towards the ward for premature contraction. She gave a 3-days history of reduced fetal movement. Antenatally, she attended antenatal check up in an additional hospital. She was mildly anaemic with haemoglobin of 10.8 g/dL and was treated with oral haematinics. Otherwise it was uneventful. She not too long ago moved to Kuala Lumpur, hence had in no way attended antenatal adhere to up in this hospital. Each her and her h.