Ochem. 2008;107(4):1091?01. https:// doi.org/10.1111/j.1471-4159.2008.05687.x.38. Broughton BR, Brait VH
Ochem. 2008;107(4):1091?01. https:// doi.org/10.1111/j.1471-4159.2008.05687.x.38. Broughton BR, Brait VH, Kim HA, Lee S, Chu HX, Gardiner-Mann CV, et al. Sex-dependent effects of G protein-coupled estrogen receptor activity on outcome after ischemic stroke. Stroke. 2014;45(3):835?1. https://doi. org/10.1161/STROKEAHA.113.001499. 39. Abbott NJ, Patabendige AA, Dolman DE, Yusof SR, Begley DJ. Structure and function of the blood-brain barrier. Neurobiol Dis. 2010;37(1):13?5. https://doi.org/10.1016/j.nbd.2009.07.030. 40. Sashindranath M, Sales E, Daglas M, Freeman R, Samson AL, Cops EJ, et al. The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans. Brain. 2012;135(Pt 11):3251?4. https://doi. org/10.1093/brain/aws178. 41. Ishiguro M, Mishiro K, Fujiwara Y, Chen H, Izuta H, Tsuruma K, et al. Phosphodiesterase-III inhibitor prevents hemorrhagic transformation induced by focal cerebral PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/25609842 ischemia in mice treated with tPA. PLoS ONE. 2010;5(12):e15178. https://doi.org/10.1371/journal.pone.0015178. 42. Mao L, Li P, Zhu W, Cai W, Liu Z, Wang Y, et al. Regulatory T cells ameliorate PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/27362935 tissue plasminogen activator-induced brain haemorrhage after stroke. Brain. 2017;140(7):1914?1. https://doi.org/10.1093/brain/awx111. 43. Carmichael ST. Rodent models of focal stroke: size, mechanism, and purpose. NeuroRx. 2005;2(3):396?09. https://doi.org/10.1602/ neurorx.2.3.396. 44. Marcos-Contreras OA, Martinez de Lizarrondo S, Bardou I, Orset C, Pruvost M, Anfray A, et al. Hyperfibrinolysis increases blood-brain barrier permeability by a plasmin- and bradykinin-dependent mechanism. Blood. 2016;128(20):2423?4. https://doi.org/10.1182/blood-2016-03-705384. 45. Yao Y, Tsirka SE. Truncation of monocyte chemoattractant protein 1 by plasmin promotes blood-brain barrier disruption. J Cell Sci. 2011;124(Pt 9):1486?5. https://doi.org/10.1242/jcs.082834. 46. Niego B, Lee N, Larsson P, De Silva TM, Au AE, McCutcheon F, et al. Selective inhibition of brain endothelial Rho-kinase-2 provides optimal protection of an in vitro blood-brain barrier from tissue-type plasminogen activator and plasmin. PLoS ONE. 2017;12(5):e0177332. https://doi. org/10.1371/journal.pone.0177332. 47. Samson AL, Medcalf RL. Tissue-type plasminogen activator: a multifaceted modulator of neurotransmission and synaptic plasticity. Neuron. 2006;50(5):673?. https://doi.org/10.1016/j.neuron.2006.04.013.Submit your next manuscript to BioMed Central and we will help you at every step:?We accept pre-submission inquiries ?Our selector tool helps you to find the most relevant journal ?We provide round the clock customer support ?Convenient online submission ?Thorough peer review ?Inclusion in PubMed and all major indexing services ?Maximum visibility for your research Submit your manuscript at www.biomedcentral.com/submit
Ren et al. Mol Pain (2015) 11:37 DOI 10.1186/s12990-015-0043-RESEARCHOpen AccessFunction and postnatal changes of dural SynergisidinMedChemExpress Brefeldin A afferent fibers expressing TRPM8 channelsLynn Ren1, Ajay Dhaka2 and YuQing Cao1*Abstract Background: Genomewide association studies have identified TRPM8 (transient receptor potential melastatin 8) as one of the susceptibility genes for common migraine. Here, we investigated the postnatal changes of TRPM8express ing dural afferent fibers as well as the function of dural TRPM8 channels in mice. Results: First, we quantified the density and the number of axonal branches of TRPM8express.
