Product Name: YO-01027
Chemical Name: (S)-2-(2-(3,5-difluorophenyl)acetamido)-N-((S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)propanamide
SMILES Code: C[C@H](NC(CC1=CC(F)=CC(F)=C1)=O)C(N[C@@H]2C(N(C)C3=CC=CC=C3C4=CC=CC=C24)=O)=O
CAS NO: 2492-87-7 Product: PFK-015
Synonym: Dibenzazepine; YO 01027; YO01027
Chemical Formula: C26H23F2N3O3
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Epigenetics_Compound_Library inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: YO-01027 (Dibenzazepine) is a dipeptidic γ-secretase inhibitor with IC50 of 2.6 nM and 2.9 nM in cell-free assays for APPL and Notch cleavage, respectively. γ-Secretase is a fascinating, multi-subunit, intramembrane cleaving protease that is now being conPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17124594
