Product Name: XMD8-87
Chemical Name: 2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-11-methyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one
SMILES Code: C1=NC(NC2=CC=C(N3CCN(C)CC3)C=C2OC)=NC2N(C)C3C=CC=CC=3C(=O)NC1=2
CAS NO: 91940-87-3 Product: LY-2584702 (hydrochloride)
Synonym: XMD-8-87; XMD 8-87; XMD887; XMD-887; XMD 887
Chemical Formula: C24H27N7O2
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Adenosine Kinase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: XMD8-87 is a TNK2 inhibitor. XMD8-87 showed activity in the inhibition of TNK2 phosphorylation. XMD8-87 and XMD16-5 potently inhibit phosphorylation of TNK2 truncation mutations found in solid tumor types.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17900801
