Product Name: XMD16-5
Chemical Name: 2-((4-(4-hydroxypiperidin-1-yl)phenyl)amino)-11-methyl-5,11-dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-one
SMILES Code: OC(CC1)CCN1C(C=C2)=CC=C2NC3=NC=C4C(N(C)C(C=CC=C5)=C5C(N4)=O)=N3
CAS NO: 21416-43-3 Product: LY-2584702 (tosylate salt)
Synonym: XMD-16-5; XMD 16-5; XMD165; XMD-165
Chemical Formula: C23H24N6O2
Appearance: Solid powderWeb Site：Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Aldehyde Dehydrogenase ALDH) inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: XMD16-5 is a tyrosine kinase nonreceptor 2(TNK2) inhibitor. TNK2 mutations have been found in renal cancer cells and also in lung, ovarian and gastric cancers. TNK2 genomic amplification has been associated with late stage or metastatic lung and prostate PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/9574517
