Product Name: WHI-P180
Chemical Name: 3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
SMILES Code: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)O)OC
CAS NO: 1394854-52-4 Product: Fabomotizole
Synonym: Janex 3; WHI-P 180
Chemical Formula: C16H15N3O3
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).NO Synthase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively. WHI-P180 moderately inhibited ABCG2 function, exhibiting weak phototoxicity.The elimination half-life of WHI-P180 in CD-1 mice (BALB/ c mice) following i.v.PubMed ID:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1131105/