Product Name: Vandetanib
Chemical Name: N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
SMILES Code: CN1CCC(COC2=CC3=NC=NC(NC4=CC=C(Br)C=C4F)=C3C=C2OC)CC1
CAS NO: 1257-08-5 Product: Corylifol A
Synonym: ZD6474; ZD-6474; ZD 6474
Chemical Formula: C22H24BrFN4O2
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).CRTH2 GPR44) inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 with IC50 of 40 nM in a cell-free assay. It also inhibits VEGFR3 and EGFR with IC50 of 110 nM and 500 nM, respectively. This agent also blocks the tyrosine kinase activity of epidermal growth factor recePubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21615676