Product Name: VPS34 inhibitor 1
Chemical Name: 1-[[2-[(2-chloro-4-pyridinyl)amino]-4′-(cyclopropylmethyl)[4,5′-bipyrimidin]-2′-yl]amino]-2-methyl-2-propanol
SMILES Code: OC(C)(C)CNC1=NC(CC2CC2)=C(C3=CC=NC(NC4=CC=NC(Cl)=C4)=N3)C=N1
CAS NO: 489-32-7 Product: Bay-K-8644 ((S)-(-)-)
Synonym: Vps34-IN1, Compound 19, PIK-III analogue
Chemical Formula: C21H24ClN7O
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).iGluR inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: VPS34 inhibitor 1 (Vps34-IN1, Compound 19, PIK-III analogue) is a potent and selective inhibitor of VPS34 with an IC50 of 15 nM. It does not significantly inhibit the activity of over 340 additional kinases, including class I and II PI3Ks. Vps34-IN1 inducPubMed ID:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194615/
