Product Name: UMI-77
Chemical Name: 2-((4-((4-bromophenyl)sulfonamido)-1-hydroxynaphthalen-2-yl)thio)acetic acid
SMILES Code: C1=CC=C2C(=C1)C(=CC(=C2O)SCC(=O)O)NS(=O)(=O)C3=CC=C(C=C3)Br
CAS NO: 120014-06-4 Product: Fasudil
Synonym: UMI77; UMI 77
Chemical Formula: C18H14BrNO5S2
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Toll-like Receptor TLR) inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: UMI-77 is a novel selective Mcl-1 SMI inhibitor. It binds to the BH3 binding groove of Mcl-1 with Ki of 490 nM, showing selectivity over other members of anti-apoptotic Bcl-2 members.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/10460808
